Linked Life Data

2037771

Source:http://linkedlifedata.com/resource/pubmed/id/2037771

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-7-2
pubmed:abstractText
Segments of the intestinal wall from the guinea-pig and rat were dissected, and laminae from the submucous layer subjected to light microscopic [3H]GABA autoradiography. The laminae were carefully prepared so that their planar arrangement could be easily viewed. Intense labelling of fine processes by [3H]GABA was found in the different laminae of the submucous including Henle's or Schabadasch's plexus, the vascular nerve plexus, and a network of fibres subjacent to the muscularis mucosae. This labelling was extensive and represented neuronal-specific high-affinity uptake of radiolabelled GABA. The pattern of labelling was different between the laminae; however, within individual laminae, the distribution of labelled fibres was characteristic of the local nerve networks. Ganglia displayed intense labelling of neuropil and ganglion cells. These results provide strong evidence for the presence of GABAergic nerve cells and processes in the mammalian intestinal submucosa.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0165-1838
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
251-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
High-affinity uptake of [3H]GABA by submucous ganglion cells, nerve fibres and peri- and para-vascular fibres in guinea-pig and rat intestine.
pubmed:affiliation
Department of Physiology, University of Ottawa, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't