Linked Life Data

20377307

Source:http://linkedlifedata.com/resource/pubmed/id/20377307

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-4-9
pubmed:abstractText
Infections with the opportunistic mold Aspergillus fumigatus show high morbidity and mortality. Risk factors for the development of invasive aspergillosis are neutropenia, T-cell depletion, CD34-selected stem cell products, corticosteroid therapy, and cytomegalovirus infections. Recently, a growing number of defined single nucleotide polymorphisms have been described that genetically determine susceptibility to A. fumigatus. This includes genes encoding for cytokines or chemokines and their receptors, toll-like receptor genes, and other genes involved in innate immunity. This review summarizes the current knowledge about the growing number of genetic markers and their relevance for the course and outcome of infections with A. fumigatus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1549-7828
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
168-77
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Genetic susceptibility to infections with Aspergillus fumigatus.
pubmed:affiliation
Julius-Maximilians-Universität Würzburg, Medizinische Klinik & Poliklinik II, 97070 Würzburg, Germany.
pubmed:publicationType
Journal Article, Review