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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002006,
umls-concept:C0013216,
umls-concept:C0017262,
umls-concept:C0030705,
umls-concept:C0035094,
umls-concept:C0185117,
umls-concept:C0456603,
umls-concept:C0683154,
umls-concept:C0857121,
umls-concept:C1335616,
umls-concept:C2911684
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2010-4-16
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|
pubmed:abstractText |
RGS2 (regulators of G-protein signalling) is a negative regulator of Galphaq protein signalling, which mediates the action of several vasoconstrictors. Low RGS2 expression increases G-protein-coupled signalling in hypertensive patients. The aim of the present study was to correlate RGS2 expression in peripheral blood mononuclear cells (PBMs) with response to antihypertensive therapy in never-treated patients with essential hypertension.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
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pubmed:issn |
1473-5598
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
28
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1104-8
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pubmed:meshHeading |
pubmed-meshheading:20375904-Adolescent,
pubmed-meshheading:20375904-Adult,
pubmed-meshheading:20375904-Aged,
pubmed-meshheading:20375904-Aldosterone,
pubmed-meshheading:20375904-Antihypertensive Agents,
pubmed-meshheading:20375904-Blood Pressure,
pubmed-meshheading:20375904-Cohort Studies,
pubmed-meshheading:20375904-Drug Resistance,
pubmed-meshheading:20375904-Feedback, Physiological,
pubmed-meshheading:20375904-Female,
pubmed-meshheading:20375904-Gene Expression,
pubmed-meshheading:20375904-Humans,
pubmed-meshheading:20375904-Hypertension,
pubmed-meshheading:20375904-Male,
pubmed-meshheading:20375904-Middle Aged,
pubmed-meshheading:20375904-RGS Proteins,
pubmed-meshheading:20375904-RNA, Messenger,
pubmed-meshheading:20375904-Renin,
pubmed-meshheading:20375904-Young Adult
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|
pubmed:year |
2010
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pubmed:articleTitle |
RGS2 expression and aldosterone: renin ratio modulate response to drug therapy in hypertensive patients.
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|
pubmed:affiliation |
Clinica Medica 4, Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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