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rdf:type |
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lifeskim:mentions |
umls-concept:C0001811,
umls-concept:C0018284,
umls-concept:C0029408,
umls-concept:C0035647,
umls-concept:C0178539,
umls-concept:C0225369,
umls-concept:C0302600,
umls-concept:C0311402,
umls-concept:C0379710,
umls-concept:C1314939,
umls-concept:C1514559
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pubmed:issue |
2
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pubmed:dateCreated |
2010-4-8
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pubmed:abstractText |
Recently, attention has been attracted by the finding that overexpression of caveolin-1 induces cellular senescence in age-related diseases. We aimed to ascertain whether angiogenic growth factors (AGFs) can inhibit interleukin (IL)-1beta-induced senescence in human chondrocytes by downregulation of caveolin-1.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CAV1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Caveolin 1,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP...,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatocyte Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1beta,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/VEGFA protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1756-185X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
90-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20374325-Caveolin 1,
pubmed-meshheading:20374325-Cell Aging,
pubmed-meshheading:20374325-Cells, Cultured,
pubmed-meshheading:20374325-Chondrocytes,
pubmed-meshheading:20374325-Down-Regulation,
pubmed-meshheading:20374325-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:20374325-Fibroblast Growth Factor 2,
pubmed-meshheading:20374325-Hepatocyte Growth Factor,
pubmed-meshheading:20374325-Humans,
pubmed-meshheading:20374325-Immunohistochemistry,
pubmed-meshheading:20374325-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:20374325-Interleukin-1beta,
pubmed-meshheading:20374325-MAP Kinase Signaling System,
pubmed-meshheading:20374325-Osteoarthritis,
pubmed-meshheading:20374325-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:20374325-Stress, Physiological,
pubmed-meshheading:20374325-Vascular Endothelial Growth Factor A,
pubmed-meshheading:20374325-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2009
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pubmed:articleTitle |
Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing.
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pubmed:affiliation |
Department of Frontier Medicine, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan. yudo@marianna-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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