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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-5-11
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pubmed:abstractText |
To determine the effect of exogenous oxytocin (OT) administration on inflammation and atherosclerosis in socially isolated apoE(-/-) mice. Hyperlipidemic animals housed in isolated or stressful social environments display more extensive atherosclerosis than those in an affiliative social environment. The neurohypophyseal peptide OT may be involved in both affiliative social behavior and cardiovascular homeostasis, suggesting a role in mediating the benefits of positive social interactions on atherosclerosis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1534-7796
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
376-82
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pubmed:meshHeading |
pubmed-meshheading:20368478-Adipose Tissue,
pubmed-meshheading:20368478-Animals,
pubmed-meshheading:20368478-Aorta, Thoracic,
pubmed-meshheading:20368478-Apolipoproteins E,
pubmed-meshheading:20368478-Atherosclerosis,
pubmed-meshheading:20368478-Disease Models, Animal,
pubmed-meshheading:20368478-Inflammation,
pubmed-meshheading:20368478-Interleukin-6,
pubmed-meshheading:20368478-Male,
pubmed-meshheading:20368478-Mice,
pubmed-meshheading:20368478-Oxytocin,
pubmed-meshheading:20368478-Receptors, Oxytocin,
pubmed-meshheading:20368478-Social Isolation,
pubmed-meshheading:20368478-Sympathetic Nervous System
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pubmed:year |
2010
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|
pubmed:articleTitle |
Oxytocin attenuates atherosclerosis and adipose tissue inflammation in socially isolated ApoE-/- mice.
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pubmed:affiliation |
Department of Psychiatry, University of California, San Diego, School of Medicine, San Diego, California, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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