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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-5-18
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pubmed:abstractText |
Bovine-origin Escherichia coli isolates were tested for resistance phenotypes using a disk diffusion assay and for resistance genotypes using a DNA microarray. An isolate with gentamicin and amikacin resistance but with no corresponding genes detected yielded a 1,056-bp DNA sequence with the closest homologues for its inferred protein sequence among a family of 16S rRNA methyltransferase enzymes. These enzymes confer high-level aminoglycoside resistance and have only recently been described in Gram-negative bacteria.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1098-6596
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2666-9
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pubmed:dateRevised |
2011-3-3
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pubmed:meshHeading |
pubmed-meshheading:20368404-Animals,
pubmed-meshheading:20368404-Base Sequence,
pubmed-meshheading:20368404-Cattle,
pubmed-meshheading:20368404-DNA, Bacterial,
pubmed-meshheading:20368404-DNA Primers,
pubmed-meshheading:20368404-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:20368404-Escherichia coli,
pubmed-meshheading:20368404-Genes, Bacterial,
pubmed-meshheading:20368404-Methyltransferases,
pubmed-meshheading:20368404-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20368404-Phylogeny,
pubmed-meshheading:20368404-RNA, Bacterial,
pubmed-meshheading:20368404-RNA, Ribosomal, 16S
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pubmed:year |
2010
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pubmed:articleTitle |
Discovery of a gene conferring multiple-aminoglycoside resistance in Escherichia coli.
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pubmed:affiliation |
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164-7040, USA. madavis@vetmed.wsu.edu
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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