Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Pt 2
pubmed:dateCreated
2010-4-6
pubmed:abstractText
We report theory and numerical simulations that demonstrate the feasibility of simultaneous reconstruction of the three-dimensional scattering and absorption coefficients of a mesoscopic system using angularly resolved measurements of scattered light. Image reconstruction is based on the inversion of a generalized (broken ray) Radon transform relating the scattering and absorption coefficients of the medium to angularly resolved intensity measurements. Although the single-scattering approximation to the radiative transport equation (RTE) is used to devise the image reconstruction method, there is no assumption that only singly scattered light is measured. That is, no physical mechanism for separating single-scattered photons from the rest of the multiply-scattered light (e.g., time gating) is employed in the proposed experiments. Numerical examples of image reconstruction are obtained using samples of optical depth of up to 3.2. The forward data are obtained from numerical solution of the RTE, accounting for all orders of scattering.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1550-2376
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
016602
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Single-scattering optical tomography: simultaneous reconstruction of scattering and absorption.
pubmed:affiliation
Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, N.I.H., Extramural