Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-4-5
pubmed:abstractText
An optical projection tomography microscope (OPTM) can improve axial resolution by viewing a sample from different perspectives. Here, we report a dual-mode OPTM that can generate 3D images of single cancer cells in both absorption mode and polarization mode. Cancer cells were labeled with hematoxylin for absorption imaging and nanorods for polarization imaging. Absorption images can provide morphologic information, and polarization images can provide molecular information. The combination of molecular detection and 3D cytological cell analysis may help with early cancer diagnosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1539-4794
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1037-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Dual-mode optical projection tomography microscope using gold nanorods and hematoxylin-stained cancer cells.
pubmed:affiliation
Department of Bioengineering, University of Washington, NE Pacific St., Seattle, Washington 98195, USA. miaoq@u.washington.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't