rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-5-10
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pubmed:abstractText |
In this review, the role of anti-Müllerian hormone (AMH) as a regulator and marker of ovarian function is described. Studies in mice showed that AMH is one of the intra-ovarian growth factors regulating primordial follicle recruitment and follicle-stimulating hormone (FSH) sensitivity of growing follicles in an inhibitory manner. Association studies of common variants of the AMH and AMHRII gene suggest that AMH may have a similar role in the human ovary. When it was discovered that serum levels AMH are correlated with the number of growing follicles, AMH gained further clinical interest as a marker for the quantitative aspect of ovarian reserve and as a diagnostic marker for polycystic ovary syndrome (PCOS).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0003-4266
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2010 Elsevier Masson SAS. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
191-7
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pubmed:meshHeading |
pubmed-meshheading:20362961-Animals,
pubmed-meshheading:20362961-Anti-Mullerian Hormone,
pubmed-meshheading:20362961-Female,
pubmed-meshheading:20362961-Genotype,
pubmed-meshheading:20362961-Homeostasis,
pubmed-meshheading:20362961-Humans,
pubmed-meshheading:20362961-Mice,
pubmed-meshheading:20362961-Mice, Knockout,
pubmed-meshheading:20362961-Mullerian Ducts,
pubmed-meshheading:20362961-Ovarian Follicle,
pubmed-meshheading:20362961-Ovary,
pubmed-meshheading:20362961-Receptors, Peptide,
pubmed-meshheading:20362961-Receptors, Transforming Growth Factor beta
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pubmed:year |
2010
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pubmed:articleTitle |
Anti-Müllerian hormone (AMH): regulator and marker of ovarian function.
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pubmed:affiliation |
Department of Internal Medicine, Room Ee532, Erasmus MC, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Review
|