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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2010-5-14
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pubmed:abstractText |
Polyploidy and multinucleation are characteristic features of mammalian cardiomyocytes, which develop shortly after birth when most differentiated cardiomyocytes become acytokinetic. Cardiac overload and hypertrophy further increase the degree of polyploidy of cardiomyocytes, suggesting a role in cell type-specific responses to physiological and pathological stimuli.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4571
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1498-506
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pubmed:meshHeading |
pubmed-meshheading:20360255-Animals,
pubmed-meshheading:20360255-Cell Proliferation,
pubmed-meshheading:20360255-Cyclin G1,
pubmed-meshheading:20360255-Gene Expression Profiling,
pubmed-meshheading:20360255-Mice,
pubmed-meshheading:20360255-Mice, Inbred C57BL,
pubmed-meshheading:20360255-Mice, Knockout,
pubmed-meshheading:20360255-Myocytes, Cardiac,
pubmed-meshheading:20360255-Polyploidy,
pubmed-meshheading:20360255-Rats,
pubmed-meshheading:20360255-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2010
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pubmed:articleTitle |
Regulation of cardiomyocyte polyploidy and multinucleation by CyclinG1.
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pubmed:affiliation |
Max-Planck-Institut for Heart und Lung Research, D-61231 Bad Nauheim, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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