Source:http://linkedlifedata.com/resource/pubmed/id/20359436
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-4-2
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pubmed:abstractText |
To determine the association between Human papillomavirus (HPV)-type infections with the frequency of Micronucleus (MN), a hospital-based, unmatched case-control study was carried out. We evaluated and compared the average number of MN/1,000 cells among three groups of Mexican females. Twenty one women ranging in age from 31-56 years and divided into three groups were studied. Group I comprised seven control women without cervical lesions and with HPV-negative, Group II was composed of seven women with Squamous intraepithelial lesions (SIL) infected with low-risk HPV low-risk, and Group III was made up of seven women with SIL infected with high-risk HPV infection. Analysis of variance (ANOVA) test revealed differences among Groups I (5.14+/-3.02), II (13.43+/-3.41), and III (25.43+/-3.41) (F=67.46; P=0.0001). We demonstrated an association between HPV type infection and higher MN frequencies. However, a larger controlled study with sufficient follow-up will be required to further evaluate the usefulness of this test in the clinical management of women with HPV infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1214-6994
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-41
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pubmed:meshHeading |
pubmed-meshheading:20359436-Adult,
pubmed-meshheading:20359436-Cervical Intraepithelial Neoplasia,
pubmed-meshheading:20359436-DNA, Viral,
pubmed-meshheading:20359436-Female,
pubmed-meshheading:20359436-Genotype,
pubmed-meshheading:20359436-Humans,
pubmed-meshheading:20359436-Micronucleus Tests,
pubmed-meshheading:20359436-Middle Aged,
pubmed-meshheading:20359436-Papillomaviridae,
pubmed-meshheading:20359436-Papillomavirus Infections,
pubmed-meshheading:20359436-Polymerase Chain Reaction,
pubmed-meshheading:20359436-Uterine Cervical Neoplasms,
pubmed-meshheading:20359436-Vaginal Smears
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pubmed:year |
2010
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pubmed:articleTitle |
Association between human papilloma virus-type infections with micronuclei frequencies.
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pubmed:affiliation |
División de Genética, Centro de Investigación Biomédica del Noreste, IMSS, Monterrey, México. elvacortes@cibinmty.net
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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