Source:http://linkedlifedata.com/resource/pubmed/id/20352594
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2010-3-30
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pubmed:abstractText |
In this case report we present a 61-year-old patient with obstructive jaundice. Bile duct obstruction was caused by a tumor at the duodenal papilla and bile flow was restored by a plastic stent. Using endoscopic ultrasound and computed tomography imaging two additional tumors of the same morphology were found in the stomach wall and the pelvic region suggesting a multilocular gastrointestinal stroma tumor (GIST). Diagnosis of GIST was confirmed cytologically from the gastric lesion. Based on typical cutaneous manifestations (café-au-lait spots, several tiny dermal neurofibromata and Lisch nodules in the iris), a thus far unidentified neurofibromatosis type I was diagnosed which is known to promote multilocular GIST formation. Tumor resection failed because of cardiac decompensation due to a Takotsubo cardiomyopathy during induction of anesthesia. The patient has been started on imatinib instead and shows so far a stable disease over 6 months.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1439-7803
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
479-81
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pubmed:meshHeading |
pubmed-meshheading:20352594-Cholestasis, Extrahepatic,
pubmed-meshheading:20352594-Diagnosis, Differential,
pubmed-meshheading:20352594-False Negative Reactions,
pubmed-meshheading:20352594-Gastrointestinal Stromal Tumors,
pubmed-meshheading:20352594-Humans,
pubmed-meshheading:20352594-Male,
pubmed-meshheading:20352594-Middle Aged,
pubmed-meshheading:20352594-Neurofibromatosis 1
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pubmed:year |
2010
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pubmed:articleTitle |
Gastrointestinal stromal tumor in a patient with undiagnosed neurofibromatosis type I: an uncommon cause of extrahepatic cholestasis.
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pubmed:affiliation |
Department of Internal Medicine, Salem Medical Center, University of Heidelberg, Heidelberg, Germany. gunda.millonig@uni-heidelberg.de
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pubmed:publicationType |
Journal Article,
Case Reports
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