Linked Life Data

20350012

Source:http://linkedlifedata.com/resource/pubmed/id/20350012

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-3-30
pubmed:abstractText
The composite silver and gold nanoparticles (AgNPs and AuNPs) coated with nonionic amphiphilic block copolymers (Pluronics L121, F68, or F127) are prepared by their adsorption under critical micelle concentrations. It is found that Pluronics bind to the surface of metal NPs as a very thin film by the hydrophobic association through poly(propylene oxide) block of the copolymers. The modification increases the colloidal stability of NPs with increasing hydrophilic-lipophilic balance of Pluronics in the order of L121, F127, and F68. In order to investigate the potentials of polymer coated noble metal NPs as surface-enhanced Raman spectroscopy (SERS) probes, fluorescent dyes and doxorubicin are used as model compounds. It is found that Pluronic component promotes the adsorption of these compounds on the composite NPs resulting in a considerable increase of Raman signal. This effect is attributed to increased concentration of the analyte molecules on the composite surface due to the hydrophobic and charge-charge interactions between the analytes and the Pluronic coat, and the stabilization of NPs by poly(ethylene oxide) blocks. The copolymer coated AgNPs show higher SERS activity than the counterparts prepared with AuNPs. Among the prepared composites, the AgNPs modified with Pluronic F127 containing extended poly(propylene oxide) and poly(ethylene oxide) blocks exhibit maximal Raman activity using rhodamine 6G (Rh6G) with a EF of 9.04 x 10(6). The results show that the developed Pluronic-based SERS probes can be used for sensitive and selective analysis of organic analytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1520-5827
pubmed:author
pubmed:issnType
Electronic
pubmed:day
6
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5153-9
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Pluronic block copolymer-mediated interactions of organic compounds with noble metal nanoparticles for SERS analysis.
pubmed:affiliation
Faculty of Biology and Soil Sciences, Kazan State University, Kazan, Tatarstan, Russia. tabdulli@gmail.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't