| pubmed-article:20349263 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20349263 | lifeskim:mentions | umls-concept:C0036751 | lld:lifeskim |
| pubmed-article:20349263 | lifeskim:mentions | umls-concept:C0379900 | lld:lifeskim |
| pubmed-article:20349263 | lifeskim:mentions | umls-concept:C1155354 | lld:lifeskim |
| pubmed-article:20349263 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:20349263 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:20349263 | lifeskim:mentions | umls-concept:C0323351 | lld:lifeskim |
| pubmed-article:20349263 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:20349263 | pubmed:dateCreated | 2010-6-22 | lld:pubmed |
| pubmed-article:20349263 | pubmed:abstractText | Serotonin plays a key role in modulating various physiological and behavioral processes in both protostomes and deuterostomes. The vast majority of serotonin receptors belong to the superfamily of G-protein-coupled receptors. We report the cloning of a cDNA from the honeybee (Am5-ht1A) sharing high similarity with members of the 5-HT(1) receptor class. Activation of Am5-HT(1A) by serotonin inhibited the production of cAMP in a dose-dependent manner (EC(50) = 16.9 nM). Am5-HT(1A) was highly expressed in brain regions known to be involved in visual information processing. Using in vivo pharmacology, we could demonstrate that Am5-HT(1A) receptor ligands had a strong impact on the phototactic behavior of individual bees. The data presented here mark the first comprehensive study-from gene to behavior-of a 5-HT(1A) receptor in the honeybee, paving the way for the eventual elucidation of additional roles of this receptor subtype in the physiology and behavior of this social insect. | lld:pubmed |
| pubmed-article:20349263 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20349263 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20349263 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20349263 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:20349263 | pubmed:issn | 1420-9071 | lld:pubmed |
| pubmed-article:20349263 | pubmed:author | pubmed-author:ScheinerRicar... | lld:pubmed |
| pubmed-article:20349263 | pubmed:author | pubmed-author:BlenauWolfgan... | lld:pubmed |
| pubmed-article:20349263 | pubmed:author | pubmed-author:BaumannArndA | lld:pubmed |
| pubmed-article:20349263 | pubmed:author | pubmed-author:BalfanzSabine... | lld:pubmed |
| pubmed-article:20349263 | pubmed:author | pubmed-author:ThammMarkusM | lld:pubmed |
| pubmed-article:20349263 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20349263 | pubmed:volume | 67 | lld:pubmed |
| pubmed-article:20349263 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20349263 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20349263 | pubmed:pagination | 2467-79 | lld:pubmed |
| pubmed-article:20349263 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:meshHeading | pubmed-meshheading:20349263... | lld:pubmed |
| pubmed-article:20349263 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20349263 | pubmed:articleTitle | Characterization of the 5-HT1A receptor of the honeybee (Apis mellifera) and involvement of serotonin in phototactic behavior. | lld:pubmed |
| pubmed-article:20349263 | pubmed:affiliation | Institute of Biochemistry and Biology, Animal Physiology, University of Potsdam, Potsdam, Germany. | lld:pubmed |
| pubmed-article:20349263 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20349263 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:410435 | entrezgene:pubmed | pubmed-article:20349263 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20349263 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20349263 | lld:pubmed |
