Linked Life Data

20329790

Source:http://linkedlifedata.com/resource/pubmed/id/20329790

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-4-9
pubmed:abstractText
The dearomatization reaction of benzylic chlorides (1a-k), chloromethylnaphthalenes (1l-r), and naphthalene allyl chlorides (3a-d) with allenyltributyltin proceeded smoothly in the presence of Pd(PPh(3))(4) catalyst at room temperature to give the corresponding propargylated and/or allenylated dearomatization products (5, 5'; 6, 6'; and 7, respectively) in high to fair yields. The reaction of 1a-k proceeded smoothly in the presence of TBAF, whereas it was not necessary to use TBAF as an additive in the reactions of 1l-k and 3a-d. These reactions provided a new and efficient method for the synthesis of propargylic and allenic carbocycles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1520-6904
pubmed:author
pubmed:issnType
Electronic
pubmed:day
16
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2619-27
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Propargylic and allenic carbocycle synthesis through palladium-catalyzed dearomatization reaction.
pubmed:affiliation
State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't