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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1991-6-24
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pubmed:abstractText |
In 19 patients with advanced pretreated breast cancer, vinblastine was administered by continuous venous infusion (2 mg/m2/24 h for 120 h every 3 weeks), using a totally implanted venous access and a portable pump. A total of 55 courses were given. Five objective responses were observed. Drug-related toxicity consisted mainly of leukopenia (4 patients), fever (4 patients) and nausea and vomiting (3 patients). Catheter-related toxicity was observed in 4 patients (21%) and consisted of infection of the skin pocket in 1 patient and dislodging of the needle with drug extravasation in 3 patients.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0009-3157
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
37
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
146-9
|
pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:2032471-Adult,
pubmed-meshheading:2032471-Breast Neoplasms,
pubmed-meshheading:2032471-Female,
pubmed-meshheading:2032471-Humans,
pubmed-meshheading:2032471-Infusions, Intravenous,
pubmed-meshheading:2032471-Middle Aged,
pubmed-meshheading:2032471-Neoplasm Metastasis,
pubmed-meshheading:2032471-Vinblastine
|
pubmed:year |
1991
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pubmed:articleTitle |
Continuous venous infusion of vinblastine in metastatic breast cancer.
|
pubmed:affiliation |
Istituo Nazionale per la Ricerca sul Cancro, Genova, Italia.
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pubmed:publicationType |
Journal Article,
Clinical Trial
|