Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1978-3-10
|
pubmed:abstractText |
An in vitro method was used to induce non-productive herpes simplex virus type 2 (HSV-2) infections in human ecto- and endocervical epithelial cells. Adenine arabinoside (ara-A) could prevent the replication of HSV-2 in ecto- and endocervical cells and after removal of ara-A from growth medium a rapid destruction of explants with development of infectious virus was observed. When ara-A was not withdrawn until 4 days or later after in vitro infection the morphological, immunofluorescent and virological studies detected no infections. However, 2-3 weeks after inoculation there were in some cultures morphological as well as immunofluorescent signs of HSV infection without demonstrable infectious virus, indicating an incidental abortive nature of the infective process.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0105-0656
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
85B
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
289-95
|
pubmed:dateRevised |
2009-6-4
|
pubmed:meshHeading |
pubmed-meshheading:203162-Cells, Cultured,
pubmed-meshheading:203162-Cervix Uteri,
pubmed-meshheading:203162-Epithelium,
pubmed-meshheading:203162-Female,
pubmed-meshheading:203162-Fluorescent Antibody Technique,
pubmed-meshheading:203162-Humans,
pubmed-meshheading:203162-Simplexvirus,
pubmed-meshheading:203162-Vidarabine,
pubmed-meshheading:203162-Virus Cultivation,
pubmed-meshheading:203162-Virus Replication
|
pubmed:year |
1977
|
pubmed:articleTitle |
Induction of latent Herpes simplex virus type 2 infection in human cervical epithelial cells in vitro.
|
pubmed:publicationType |
Journal Article,
In Vitro
|