Linked Life Data

20309014

Source:http://linkedlifedata.com/resource/pubmed/id/20309014

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-5-6
pubmed:abstractText
Langerhans cells (LCs) refer to the dendritic cells (DCs) that populate the epidermis. Strategically located at one of the body's largest interfaces with the external environment, they form the first line of defense against pathogens that breach the skin. Although LCs share several phenotypical and functional features with lymphoid and non-lymphoid organ DCs, they also have unique properties that distinguish them from most DC populations. In this review, we will discuss the key mechanisms that regulate LC homeostasis in quiescent and inflamed skin. We will also discuss recent evidence that suggests that LCs arise from dedicated precursors during early embryonic development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1440-1711
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
387-92
pubmed:dateRevised
2010-11-29
pubmed:meshHeading
pubmed:articleTitle
Ontogeny and homeostasis of Langerhans cells.
pubmed:affiliation
Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Immunos, Biopolis, Singapore. florent_ginhoux@immunol.a-star.edu.sg
pubmed:publicationType
Journal Article, Review