Linked Life Data

20306359

Source:http://linkedlifedata.com/resource/pubmed/id/20306359

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2011-4-4
pubmed:abstractText
Two new oleanolic acid saponins, namely celosin A (1) and celosin B (2), together with six known compounds, stigmasterol, ?-sitosterol, ?-daucosterol, hexacosoic acid, palmitic acid and stearic acid, were isolated from the ethanolic extract of Semen celosiae. The structures of celosin A (1) and celosin B (2) were determined by spectral analysis (including 1D- and 2D-NMR). The hepatoprotective activity of 1 and 2 with oral doses 1.0, 2.0 and 4.0 mg kg?¹ were investigated by carbon tetrachloride CCl?-induced hepatotoxicity in mice. The results indicate that they have significant hepatoprotective effects, and that these hepatoprotective effects may be due to the antioxidant capability.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1478-6427
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
772-80
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Two new compounds from Semen celosiae and their protective effects against CCl?-induced hepatotoxicity.
pubmed:affiliation
Pharmacognosy Department, School of Pharmacy, Second Military Medical University, Shanghai 200433, P.R. China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't