Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-4-5
pubmed:abstractText
Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase is being pursued with the assistance of free energy perturbation (FEP) calculations to predict relative free energies of binding. Extension of azole-containing inhibitors into an 'eastern' channel between Phe227 and Pro236 has led to the discovery of potent and structurally novel derivatives.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-11481007, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-11850281, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-12296734, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-1377403, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-15658855, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-15743172, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-15870211, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-16200637, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-16263277, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-16302798, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-17918923, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-18588301, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-19317443, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-19778066, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-7513427, http://linkedlifedata.com/resource/pubmed/commentcorrection/20304641-8304960
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1464-3405
pubmed:author
pubmed:copyrightInfo
Copyright 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2485-8
pubmed:dateRevised
2011-10-31
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives.
pubmed:affiliation
Department of Chemistry, Yale University, New Haven, CT 06520, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural