Linked Life Data

20304008

Source:http://linkedlifedata.com/resource/pubmed/id/20304008

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-5-5
pubmed:abstractText
Using intrinsic optical imaging methods, somatosensory-evoked neural activity was visualized in the rat barrel cortex at high spatial resolution in order to obtain cortical maps of the directional selectivity of whisker deflection. For this task, a special multidirectional mechanical stimulator was developed in our laboratory. The vibrissae were covered with magnetic paint and deflection was performed using a custom-built deflecting device with four small crosswise electromagnets; the whisker was placed at the intersection of the magnet axes. The results show that differences between responses to directional deflection were indicated by a change in the intrinsic optical signal of incident light at 546 nm corresponding to an increase in blood volume. Our results provide a preliminary indication that the different regions of the barrel have different directional preference, supporting recent electrophysiological studies suggesting that the barrel might have a fine, directionally-sensitive anatomical structure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1872-678X
pubmed:author
pubmed:copyrightInfo
(c) 2010 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
30
pubmed:volume
189
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
80-3
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Intrinsic optical imaging of directional selectivity in rat barrel cortex: application of a multidirectional magnetic whisker stimulator.
pubmed:affiliation
Department of Biomedical Engineering, Washington University in St. Louis, Campus Box 1097, One Brookings Drive, Saint-Louis, MO 63130, USA. tsytsarev@wustl.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't