Linked Life Data

20299330

Source:http://linkedlifedata.com/resource/pubmed/id/20299330

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-7-16
pubmed:abstractText
Glycogen synthase kinase 3 (GSK-3) signalling is implicated in the growth of the heart during development and in response to stress. However, its precise role remains unclear. We set out to characterize developmental growth and response to chronic isoproterenol (ISO) stress in knockin (KI) mice lacking the critical N-terminal serines, 21 of GSK-3alpha and 9 of GSK-3beta respectively, required for inactivation by upstream kinases.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-10506186, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-10645932, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-10799529, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-10880048, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-11018058, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-11156878, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-11299284, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-11382772, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-11782539, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-11884365, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-12623879, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-12668767, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-15001529, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-15020584, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-15173880, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-15559249, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-15791206, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-15905459, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-16775107, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-17012357, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-1703406, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-17292911, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-17322895, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-17543867, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-17855351, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-17901358, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-17993264, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-18204489, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-18583716, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-19027022, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-19071133, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-19106302, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-2950137, http://linkedlifedata.com/resource/pubmed/commentcorrection/20299330-91593
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1755-3245
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
494-503
pubmed:dateRevised
2011-11-2
pubmed:meshHeading
pubmed-meshheading:20299330-Adrenergic beta-Agonists, pubmed-meshheading:20299330-Age Factors, pubmed-meshheading:20299330-Animals, pubmed-meshheading:20299330-Apoptosis, pubmed-meshheading:20299330-Cardiomegaly, pubmed-meshheading:20299330-Disease Models, Animal, pubmed-meshheading:20299330-Enzyme Activation, pubmed-meshheading:20299330-Fibrosis, pubmed-meshheading:20299330-Gene Expression Regulation, pubmed-meshheading:20299330-Genotype, pubmed-meshheading:20299330-Glycogen Synthase Kinase 3, pubmed-meshheading:20299330-Heart Rate, pubmed-meshheading:20299330-Isoproterenol, pubmed-meshheading:20299330-Mice, pubmed-meshheading:20299330-Mice, Transgenic, pubmed-meshheading:20299330-Myocardial Contraction, pubmed-meshheading:20299330-Myocardium, pubmed-meshheading:20299330-Phenotype, pubmed-meshheading:20299330-Phosphorylation, pubmed-meshheading:20299330-Protein Kinase Inhibitors, pubmed-meshheading:20299330-Stroke Volume, pubmed-meshheading:20299330-Ventricular Function, pubmed-meshheading:20299330-Ventricular Remodeling
pubmed:year
2010
pubmed:articleTitle
Constitutive glycogen synthase kinase-3alpha/beta activity protects against chronic beta-adrenergic remodelling of the heart.
pubmed:affiliation
Division of Cardiology, King's College London BHF Centre, The Rayne Institute, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK.
pubmed:publicationType
Journal Article
More...