Linked Life Data

2028404

Source:http://linkedlifedata.com/resource/pubmed/id/2028404

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-6-10
pubmed:abstractText
Alkyllysophospholipids (ALP) represent a new class of cytotoxic agents. The cytotoxic potential was demonstrated by in vivo and in vitro models. In this study the interaction of the ALP Ilmofosine in combination with radiotherapy was tested in vitro using the colony forming assay. The cell lines B-16, K-562 and Meth-A were used as targets. The cell lines showed similar sensitivity to radiation therapy. The B-16 cell line proved to be resistant to Ilmofosine; the K-562 cell line showed little sensitivity whereas the Meth-A cell line was very sensitive to Ilmofosine. In the K-562 and Meth-A cell lines that were sensitive to both agents a clear addition of both effects was observed. In the case of the B-16 cell line in combination no effect was seen exceeding the pure radiation effect. No synergistic and no antagonistic effect was observed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0179-7158
pubmed:author
pubmed:issnType
Print
pubmed:volume
167
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
250-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Cytotoxicity of lipid ether ilmofosine in combination with radiotherapy in vitro].
pubmed:affiliation
Medizinische Klinik, Ruhr-Universität Bochum.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract