Linked Life Data

2028076

Source:http://linkedlifedata.com/resource/pubmed/id/2028076

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-6-10
pubmed:abstractText
The role of free radicals has been suggested in many different diseases; the molecular mechanisms of radical-induced damage have been widely investigated: the main effects on cellular components are lipid peroxidation, protein denaturation and DNA damage causing alteration in membrane functions, impaired enzyme activity and genetic alterations, including cancer. Since oxidative metabolism produces some radicals, aerobic organisms acquired a complex defensive system against radical attack, based on localization of oxidative reactions, enzymes that scavenge free radicals or their products and antioxidant vitamins. Diseases may arise from increased exposure to radicals or from impaired efficiency of protective systems. The role of oxygen radicals in cancerogenesis, alcoholic liver disease and the aging process is also briefly discussed.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0034-1193
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-44
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Free radicals in human pathology].
pubmed:affiliation
Istituto di Patologia speciale medica, Università, Verona.
pubmed:publicationType
Editorial, English Abstract