Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1991-6-12
|
| pubmed:abstractText |
Alterations in trabecular subchondral bone have been measured using a microscopic computed tomography scanner in the guinea pig hind-limb myectomy model of osteoarthritis. These bone changes can be found as early as histologic changes in cartilage. To evaluate the influence of the myectomy on the animals, a gait study was performed. This data reveals an alteration in acceleration at the foot-flat phase of gait in the operated limb only, providing early quantification of the interaction between mechanics and biology.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0380-0903
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
27
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
44-5
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2027128-Animals,
pubmed-meshheading:2027128-Biomechanics,
pubmed-meshheading:2027128-Bone and Bones,
pubmed-meshheading:2027128-Cartilage,
pubmed-meshheading:2027128-Disease Models, Animal,
pubmed-meshheading:2027128-Gait,
pubmed-meshheading:2027128-Guinea Pigs,
pubmed-meshheading:2027128-Osteoarthritis,
pubmed-meshheading:2027128-Tomography, X-Ray Computed
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Early bone changes in experimental osteoarthritis using microscopic computed tomography.
|
| pubmed:affiliation |
Department of Surgery, University of Michigan, Ann Arbor.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|