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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1978-3-10
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pubmed:abstractText |
Several factors affected the interferon sensitivity of human cytomegalovirus in human foreskin fibroblast cultures. An inoculum of infected cells was up to 300-fold less sensitive than a cell-free inoculum of equivalent input multiplicity. A 10-fold increase in the dose of infectious units of either type of inoculum was associated with a 10-fold or greater decrease in interferon sensitivity. Several aspects of the virus-cell interaction were examined and parameters indicative of cell infection were less inhibited by interferon than were those for virus replication.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-5526
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
48-55
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:202571-Acridines,
pubmed-meshheading:202571-Cell Line,
pubmed-meshheading:202571-Cytomegalovirus,
pubmed-meshheading:202571-Cytopathogenic Effect, Viral,
pubmed-meshheading:202571-Fluorescent Antibody Technique,
pubmed-meshheading:202571-Inclusion Bodies, Viral,
pubmed-meshheading:202571-Interferons,
pubmed-meshheading:202571-Viral Plaque Assay
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pubmed:year |
1978
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pubmed:articleTitle |
Factors affecting the interferon sensitivity of human cytomegalovirus.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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