Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-3-18
pubmed:abstractText
According to consensus, initiation of therapy is best based on CD4 cell count, a marker of immune status, rather than on viral load, a marker of virologic replication. For patients with advanced symptoms, treatment should be started regardless of CD4 count. However, the point during the course of HIV infection at which antiretroviral therapy (ART) is best initiated in asymptomatic patients remains unclear. Guidelines issued by various agencies provide different initiation recommendations according to resource availability. This can be confusing for clinicians and policy-makers when determining the best time to initiate therapy. Optimizing the initiation of ART is clearly complex and must, therefore, be balanced between individual and broader public health needs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1469-493X
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
CD008272
pubmed:dateRevised
2010-10-21
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Optimal time for initiation of antiretroviral therapy in asymptomatic, HIV-infected, treatment-naive adults.
pubmed:affiliation
South African Cochrane Centre, South African Medical Research Council, PO Box 19070, Tygerberg, South Africa, 7505.
pubmed:publicationType
Journal Article, Review, Meta-Analysis