|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0015127,
umls-concept:C0022702,
umls-concept:C0023884,
umls-concept:C0031715,
umls-concept:C0034802,
umls-concept:C0085862,
umls-concept:C0205263,
umls-concept:C0205369,
umls-concept:C0227525,
umls-concept:C0242275,
umls-concept:C0285558,
umls-concept:C0812228,
umls-concept:C1299583,
umls-concept:C1314792,
umls-concept:C1366765,
umls-concept:C1415043,
umls-concept:C1514485,
umls-concept:C1549571,
umls-concept:C1608386,
umls-concept:C1705328,
umls-concept:C1705341
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|
pubmed:issue |
4
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pubmed:dateCreated |
2010-4-19
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|
pubmed:abstractText |
Augmenter of liver regeneration (ALR) is a potent growth factor which supports liver regeneration in experimental animals. The aim of this study was to compare proliferation as well as the kinetics of ERK1/2 and Akt/PKB phosphorylation by recombinant human ALR (rhALR) and EGF in human hepatocytes and extrahepatic cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
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pubmed:issn |
1090-2104
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pubmed:author |
|
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pubmed:copyrightInfo |
2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
16
|
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pubmed:volume |
394
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
915-20
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pubmed:meshHeading |
pubmed-meshheading:20230786-Cell Line,
pubmed-meshheading:20230786-Cell Proliferation,
pubmed-meshheading:20230786-Cytochrome Reductases,
pubmed-meshheading:20230786-Epidermal Growth Factor,
pubmed-meshheading:20230786-Hepatocytes,
pubmed-meshheading:20230786-Humans,
pubmed-meshheading:20230786-Liver,
pubmed-meshheading:20230786-Liver Regeneration,
pubmed-meshheading:20230786-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:20230786-Phosphorylation,
pubmed-meshheading:20230786-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:20230786-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20230786-Recombinant Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner.
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pubmed:affiliation |
Department of Surgery, Ludwig-Maximilians-University of Munich Hospital Grosshadern, Munich, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study
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