pubmed-article:20230618 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20230618 | lifeskim:mentions | umls-concept:C1512977 | lld:lifeskim |
pubmed-article:20230618 | lifeskim:mentions | umls-concept:C0184511 | lld:lifeskim |
pubmed-article:20230618 | lifeskim:mentions | umls-concept:C0599566 | lld:lifeskim |
pubmed-article:20230618 | pubmed:dateCreated | 2010-3-29 | lld:pubmed |
pubmed-article:20230618 | pubmed:abstractText | The episomal replication of the prototype vector pEPI-1 depends on a transcription unit starting from the constitutively expressed Cytomegalovirus immediate early promoter (CMV-IEP) and directed into a 2000 bp long matrix attachment region sequence (MARS) derived from the human beta-interferon gene. The original pEPI-1 vector contains two mammalian transcription units and a total of 305 CpG islands, which are located predominantly within the vector elements necessary for bacterial propagation and known to be counterproductive for persistent long-term transgene expression. | lld:pubmed |
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pubmed-article:20230618 | pubmed:language | eng | lld:pubmed |
pubmed-article:20230618 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20230618 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:20230618 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20230618 | pubmed:issn | 1472-6750 | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:HaasJürgenJ | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:LippsHans JHJ | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:OgrisManfredM | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:HarbottleRich... | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:BaikerArminA | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:HaaseRudolfR | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:Vizoso... | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:WongSuet-Ping... | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:ArgyrosOresti... | lld:pubmed |
pubmed-article:20230618 | pubmed:author | pubmed-author:MagnussonTere... | lld:pubmed |
pubmed-article:20230618 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20230618 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:20230618 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20230618 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20230618 | pubmed:pagination | 20 | lld:pubmed |
pubmed-article:20230618 | pubmed:dateRevised | 2010-9-30 | lld:pubmed |
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pubmed-article:20230618 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:20230618 | pubmed:articleTitle | pEPito: a significantly improved non-viral episomal expression vector for mammalian cells. | lld:pubmed |
pubmed-article:20230618 | pubmed:affiliation | Max von Pettenkofer-Institute, University of Munich, Munich, Germany. | lld:pubmed |
pubmed-article:20230618 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:20230618 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |