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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-5-11
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pubmed:abstractText |
Brain-derived neurotrophic factor (BDNF) is a member of a neurotrophin family and is involved in many physiological functions, including cell proliferation, migration, and differentiation, and neuron survival in the human nervous system. Abnormalities of BDNF have been implicated in the pathophysiology of depression based on observations that antidepressant drugs cause increases in the levels of BDNF in rat brains and its abnormalities have appeared in the serum of depressed patients and in postmortem brains of suicide victims.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1878-4216
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
30
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
645-51
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:20227453-Adolescent,
pubmed-meshheading:20227453-Adult,
pubmed-meshheading:20227453-Bipolar Disorder,
pubmed-meshheading:20227453-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:20227453-Child,
pubmed-meshheading:20227453-Depressive Disorder,
pubmed-meshheading:20227453-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20227453-Female,
pubmed-meshheading:20227453-Gene Expression,
pubmed-meshheading:20227453-Humans,
pubmed-meshheading:20227453-Lymphocytes,
pubmed-meshheading:20227453-Male,
pubmed-meshheading:20227453-Middle Aged,
pubmed-meshheading:20227453-RNA, Messenger,
pubmed-meshheading:20227453-Regression Analysis,
pubmed-meshheading:20227453-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20227453-Severity of Illness Index
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pubmed:year |
2010
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pubmed:articleTitle |
Brain-derived neurotrophic factor gene and protein expression in pediatric and adult depressed subjects.
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pubmed:affiliation |
University of Illinois at Chicago, Department of Psychiatry (MC 912), 1601 West Taylor Street, Chicago, IL 60612, United States. gpandey@psych.uic.edu
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pubmed:publicationType |
Journal Article
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