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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19-20
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pubmed:dateCreated |
2010-4-23
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pubmed:abstractText |
Disrupted-in schizophrenia 1 (DISC1), identified in a pedigree with a familial psychosis with the chromosome translocation (1:11), is a putative susceptibility gene for psychoses such as schizophrenia and major depressive disorder (MDD). Patients with chronic fatigue syndrome (CFS) report having continuous severe fatigue and many overlapping symptoms with MDD; however, the mechanism and effective treatment of CFS are still unclear. We focused on the overlapping symptoms between CFS and MDD and performed an association study of the functional single-nucleotide polymorphism (SNP) in the DISC1 gene with CFS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1879-0631
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pubmed:author |
pubmed-author:FukudaSanaeS,
pubmed-author:HashimotoRyotaR,
pubmed-author:KaminoKouzinK,
pubmed-author:KuratsuneHirohikoH,
pubmed-author:NakatomiYasuhitoY,
pubmed-author:NishizawaYoshikiY,
pubmed-author:OhiKazutakaK,
pubmed-author:TajimaSeikiS,
pubmed-author:TakedaMasatoshiM,
pubmed-author:WatanabeYasuyoshiY,
pubmed-author:YamagutiKouziK,
pubmed-author:YasudaYukaY
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
8
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
722-5
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pubmed:meshHeading |
pubmed-meshheading:20227423-Adult,
pubmed-meshheading:20227423-Aged,
pubmed-meshheading:20227423-Aged, 80 and over,
pubmed-meshheading:20227423-Alleles,
pubmed-meshheading:20227423-Amino Acid Substitution,
pubmed-meshheading:20227423-Case-Control Studies,
pubmed-meshheading:20227423-Depressive Disorder, Major,
pubmed-meshheading:20227423-Fatigue Syndrome, Chronic,
pubmed-meshheading:20227423-Female,
pubmed-meshheading:20227423-Genotype,
pubmed-meshheading:20227423-Humans,
pubmed-meshheading:20227423-Male,
pubmed-meshheading:20227423-Middle Aged,
pubmed-meshheading:20227423-Nerve Tissue Proteins,
pubmed-meshheading:20227423-Phenotype,
pubmed-meshheading:20227423-Polymorphism, Single Nucleotide
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pubmed:year |
2010
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pubmed:articleTitle |
A functional polymorphism in the disrupted-in schizophrenia 1 gene is associated with chronic fatigue syndrome.
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pubmed:affiliation |
Department of Biomarker and Molecular Biophysics, Osaka City University Graduate School of Medicine, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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