Source:http://linkedlifedata.com/resource/pubmed/id/20227096
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
2010-8-5
|
pubmed:abstractText |
The purpose of our entomological survey was to estimate mosquito biodiversity, infectivity rates and insecticide resistance levels in Anopheles species in four study sites in a mining area with high malaria transmission in southeastern Guinea. Anopheles gambiae s.l. (77%) was the most common Anopheles collected followed by An. funestus (20%). The specimens of the An. gambiae complex were predominantly An. gambiae S form (97.6%) with 1.4% of An. gambiae M form found in Kérouané only, and 1% of An. arabiensis which was present in all four study sites. Anopheles gambiae S form and An. funestus were found to be infected with Plasmodium falciparum, with infectivity rates of 4.1% and 4.4% and inoculation rates of 0.60 and 0.19 infected bite/person/night, respectively. In addition, a high level (79%) of the knockdown resistance (kdr) L1014F mutation was reported in the populations of An. gambiae S form. The high malaria transmission that occurs in the prospected area of Guinea requires a long-term vector control programme. However, such a control programme will have to consider the presence of the kdr gene at a surprisingly high level within the dominant vector, which could reduce the expected impact of vector control.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1878-3503
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright 2010 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
104
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
484-9
|
pubmed:meshHeading |
pubmed-meshheading:20227096-Animals,
pubmed-meshheading:20227096-Anopheles,
pubmed-meshheading:20227096-Anopheles gambiae,
pubmed-meshheading:20227096-Culex,
pubmed-meshheading:20227096-Female,
pubmed-meshheading:20227096-Gene Silencing,
pubmed-meshheading:20227096-Genotype,
pubmed-meshheading:20227096-Guinea,
pubmed-meshheading:20227096-Humans,
pubmed-meshheading:20227096-Insect Vectors,
pubmed-meshheading:20227096-Insecticide Resistance,
pubmed-meshheading:20227096-Insecticides,
pubmed-meshheading:20227096-Malaria,
pubmed-meshheading:20227096-Male,
pubmed-meshheading:20227096-Mutation,
pubmed-meshheading:20227096-Polymerase Chain Reaction,
pubmed-meshheading:20227096-Sterculiaceae
|
pubmed:year |
2010
|
pubmed:articleTitle |
Entomological survey and report of a knockdown resistance mutation in the malaria vector Anopheles gambiae from the Republic of Guinea.
|
pubmed:affiliation |
Institut de Recherche pour le Développement, Ave Agropolis, 34394 Montpellier, France.
|
pubmed:publicationType |
Journal Article,
Multicenter Study
|