20227034

Source:http://linkedlifedata.com/resource/pubmed/id/20227034

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0029016, umls-concept:C1415876, umls-concept:C1415877
pubmed:issue	3
pubmed:dateCreated	2010-3-15
pubmed:abstractText	Oncogenes usually increase their normal function when activated. However, seemingly oncogenic mutations in IDH1 and IDH2 reduce their native enzyme activity. In this issue of Cancer Cell, Ward et al. pin down a neomorphic enzyme activity as a possible oncogenic function for these alterations.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/20227034-20171147
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101130617
pubmed:status	PubMed-not-MEDLINE
pubmed:month	Mar
pubmed:issn	1878-3686
pubmed:author	pubmed-author:ParsonsD WilliamsDW, pubmed-author:ReitmanZachary JZJ, pubmed-author:YanHaiH
pubmed:copyrightInfo	Copyright 2010 Elsevier Inc. All rights reserved.
pubmed:issnType	Electronic
pubmed:day	16
pubmed:volume	17
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	215-6
pubmed:year	2010
pubmed:articleTitle	IDH1 and IDH2: not your typical oncogenes.
pubmed:affiliation	The Preston Robert Tisch Brain Tumor Center at Duke, The Pediatric Brain Tumor Institute, and The Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.
pubmed:publicationType	Journal Article, Comment