Source:http://linkedlifedata.com/resource/pubmed/id/20224102
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2010-3-12
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pubmed:abstractText |
A metastatic gastric neuroendocrine carcinoma in a 2.5-year-old inland bearded dragon (Pogona vitticeps) with a chronic history of anorexia, weight loss, depression, and acute melena is described. Histologic examination of the gastric mass revealed a densely cellular tumor arranged in nests and occasional rosettes of hyperchromatic cells with oval to spindle-shaped nuclei and minimal cytoplasm; the tumor was supported by a moderate fibrovascular stroma. Similar cells invaded through the gastric mucosa, and there were multiple hepatic metastases. The neoplastic cells were weakly immunopositive for neuron-specific enolase and moderately positive for somatostatin but were negative for chromogranin AB and gastrin. Ultrastructural studies revealed scattered neurosecretory granules in the neoplastic cells, confirming the diagnosis of a neuroendocrine carcinoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1040-6387
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
316-20
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
A gastric neuroendocrine carcinoma expressing somatostatin in a bearded dragon (Pogona vitticeps).
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pubmed:affiliation |
Department of Pathobiology, 2407 River Drive, Room A201, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN 37996-4542, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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