Source:http://linkedlifedata.com/resource/pubmed/id/20223298
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2010-4-21
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pubmed:abstractText |
Rotavirus is the main cause of acute viral gastroenteritis in infants and young children worldwide. Surveillance of group A rotavirus has been conducted in Chiang Mai, Thailand since 1987 up to 2004 and those studies revealed that group A rotavirus was responsible for about 20-61% of diarrheal diseases in hospitalized cases. In this study, we reported the continuing surveillance of group A rotavirus in 2005 and found that group A rotavirus was detected in 43 out of 147 (29.3%) stool samples. Five different G and P genotype combinations were detected, G1P[8] (27 strains), G2P[4] (12 strains), G9P[8] (2 strains), G3P[8] (1 strain), and G3P[10] (1 strain). In addition, analysis of their genotypic linkages of G (VP7), P (VP4), I (VP6), E (NSP4), and H (NSP5) genotypes demonstrated that the rotaviruses circulating in Chiang Mai, Thailand carried 3 unique linkage patterns. The G1P[8], G3P[8], and G9P[8] strains carried their VP6, NSP4, NSP5 genotypes of I1, E1, H1, respectively. The G2P[4] strains were linked with I2, E2, H2 genotypes, while an uncommon G3P[10] genotype carried unique genotypes of I8, E3 and H6. These findings provide the overall picture of genotypic linkage data of rotavirus strains circulating in Chiang Mai, Thailand.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Capsid Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/NS28 protein, rotavirus,
http://linkedlifedata.com/resource/pubmed/chemical/Toxins, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/VP4 protein, Rotavirus,
http://linkedlifedata.com/resource/pubmed/chemical/VP6 protein, Rotavirus,
http://linkedlifedata.com/resource/pubmed/chemical/VP7 protein, Rotavirus,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Nonstructural Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1567-7257
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
467-72
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20223298-Acute Disease,
pubmed-meshheading:20223298-Antigens, Viral,
pubmed-meshheading:20223298-Capsid Proteins,
pubmed-meshheading:20223298-Child, Preschool,
pubmed-meshheading:20223298-Gastroenteritis,
pubmed-meshheading:20223298-Genetic Linkage,
pubmed-meshheading:20223298-Genotype,
pubmed-meshheading:20223298-Glycoproteins,
pubmed-meshheading:20223298-Humans,
pubmed-meshheading:20223298-Infant,
pubmed-meshheading:20223298-Phylogeny,
pubmed-meshheading:20223298-Rotavirus,
pubmed-meshheading:20223298-Rotavirus Infections,
pubmed-meshheading:20223298-Thailand,
pubmed-meshheading:20223298-Toxins, Biological,
pubmed-meshheading:20223298-Viral Nonstructural Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
Genotypic linkages of VP4, VP6, VP7, NSP4, NSP5 genes of rotaviruses circulating among children with acute gastroenteritis in Thailand.
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pubmed:affiliation |
Aino Health Science Center, Aino University, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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