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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-6-6
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pubmed:abstractText |
The ability of several endocrine tests to distinguish between women with and without polycystic ovaries (PCO) has been studied prospectively in a series of 65 patients with functional oligo-amenorrhoea using ultrasonography as a reference test. In terms of overall diagnostic accuracy, the free androgen index (FAI) (94%) and the progestogen challenge (89%) gave similar results (Cl = -5 to 15%) but both were significantly better than all the other tests including measurement of serum LH (69%), total testosterone (71%) and androstenedione (74%) (minimum Cl = 6 to 23%). The FAI together with LH measurement was the most accurate of the combinations (97%) but this was not significantly better than the best of the combinations incorporating the progestogen challenge (92%; Cl = -3% to 13%). Given the limited availability of the assay for SHBG, these results show that assessment of oestrogen state is a useful method for categorizing patients with functional oligo-amenorrhoea.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Androgens,
http://linkedlifedata.com/resource/pubmed/chemical/Androstenedione,
http://linkedlifedata.com/resource/pubmed/chemical/Luteinizing Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Progestins,
http://linkedlifedata.com/resource/pubmed/chemical/Testosterone
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0300-0664
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2022063-Amenorrhea,
pubmed-meshheading:2022063-Androgens,
pubmed-meshheading:2022063-Androstenedione,
pubmed-meshheading:2022063-Female,
pubmed-meshheading:2022063-Hair,
pubmed-meshheading:2022063-Humans,
pubmed-meshheading:2022063-Luteinizing Hormone,
pubmed-meshheading:2022063-Oligomenorrhea,
pubmed-meshheading:2022063-Polycystic Ovary Syndrome,
pubmed-meshheading:2022063-Predictive Value of Tests,
pubmed-meshheading:2022063-Progestins,
pubmed-meshheading:2022063-Prospective Studies,
pubmed-meshheading:2022063-Testosterone
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pubmed:year |
1991
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pubmed:articleTitle |
The diagnosis of polycystic ovaries in women with oligo-amenorrhoea: predictive power of endocrine tests.
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pubmed:affiliation |
University Department of Obstetrics and Gynaecology, Bristol Maternity Hospital, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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