pubmed-article:20219694 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20219694 | lifeskim:mentions | umls-concept:C1160389 | lld:lifeskim |
pubmed-article:20219694 | lifeskim:mentions | umls-concept:C0002351 | lld:lifeskim |
pubmed-article:20219694 | lifeskim:mentions | umls-concept:C0040690 | lld:lifeskim |
pubmed-article:20219694 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
pubmed-article:20219694 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
pubmed-article:20219694 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:20219694 | pubmed:dateCreated | 2010-5-3 | lld:pubmed |
pubmed-article:20219694 | pubmed:abstractText | Lung development depends on accurate and precise patterning of a pulmonary anlagen, consisting of both endodermally and mesodermally derived progenitor cells. In this process, the need to establish communication and control among individual cells is paramount. Transforming growth factor-beta (TGFbeta) and Wingless/int (Wnt) signaling pathways serve this need. The individual functional repertoire of the two pathways is further expanded by cross-talk and integration of signaling at multiple levels taking advantage of their hard-wired multi-component signal transduction platforms. Cross-talk creates the possibility for both specificity and versatility in signaling during development and during repair of injured tissue. Understanding the mechanics and the physiological implications of this cross-talk is necessary for therapeutic or preventive targeting of either TGFbeta or Wnt signaling pathways. | lld:pubmed |
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pubmed-article:20219694 | pubmed:language | eng | lld:pubmed |
pubmed-article:20219694 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20219694 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:20219694 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20219694 | pubmed:month | Jun | lld:pubmed |
pubmed-article:20219694 | pubmed:issn | 1878-5875 | lld:pubmed |
pubmed-article:20219694 | pubmed:author | pubmed-author:LiChanggongC | lld:pubmed |
pubmed-article:20219694 | pubmed:author | pubmed-author:MinooParvizP | lld:pubmed |
pubmed-article:20219694 | pubmed:copyrightInfo | Copyright 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
pubmed-article:20219694 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20219694 | pubmed:volume | 42 | lld:pubmed |
pubmed-article:20219694 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20219694 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20219694 | pubmed:pagination | 809-12 | lld:pubmed |
pubmed-article:20219694 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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pubmed-article:20219694 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:20219694 | pubmed:articleTitle | Cross-talk between transforming growth factor-beta and Wingless/Int pathways in lung development and disease. | lld:pubmed |
pubmed-article:20219694 | pubmed:affiliation | Division of Neonatology, Department of Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA. minoo@usc.edu | lld:pubmed |
pubmed-article:20219694 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:20219694 | pubmed:publicationType | Review | lld:pubmed |
pubmed-article:20219694 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:20219694 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |