Linked Life Data

2021535

Source:http://linkedlifedata.com/resource/pubmed/id/2021535

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-6-4
pubmed:abstractText
An in vivo 31P NMR spectrum was obtained from each of four human breast tumours. The phosphomonoester and phosphodiester region of each spectrum consisted of a broad peak. Chemical extracts from samples of each of the tumours obtained at resection were examined on a high field strength NMR system. The phosphomonoester region in the spectrum from each extract resolved into three peaks consisting of phosphocholine, phosphoethanolamine and a nucleoside monophosphate. The phosphodiester region resolved into two components, glycerophosphorylcholine and glycerophosphorylethanolamine. Comparing the in vivo and in vitro data from each tumour showed that the contribution of phosphodiester was much lower in the in vitro spectra. We believe this to be a consequence of phospholipid, which would not appear in the aqueous extract, contributing to the phosphodiester peak in vivo.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-2558272, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-2559292, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-2566851, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-2641284, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-2779424, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-2847230, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-2955082, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-3020609, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-3409237, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-3462727, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-3667610, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-3793728, http://linkedlifedata.com/resource/pubmed/commentcorrection/2021535-6477969
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0007-0920
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
514-6
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
A comparison of in vivo and in vitro 31P NMR spectra from human breast tumours: variations in phospholipid metabolism.
pubmed:affiliation
Department of Nuclear Medicine, Royal Marsden Hospital, Sutton, Surrey, UK.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't