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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-5-12
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pubmed:abstractText |
To investigate the capacity of ADAM15, a disintegrin metalloproteinase that is up-regulated in osteoarthritic (OA) cartilage, to protect chondrocytes against apoptosis induced by growth factor deprivation and genotoxic stress.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ADAM Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/ADAM15 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/CASP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CASP7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Camptothecin,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 7,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Fgfbp1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/X-Linked Inhibitor of Apoptosis...,
http://linkedlifedata.com/resource/pubmed/chemical/XIAP protein, human
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1529-0131
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1372-82
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pubmed:meshHeading |
pubmed-meshheading:20213810-ADAM Proteins,
pubmed-meshheading:20213810-Apoptosis,
pubmed-meshheading:20213810-Blood Proteins,
pubmed-meshheading:20213810-Camptothecin,
pubmed-meshheading:20213810-Carrier Proteins,
pubmed-meshheading:20213810-Caspase 3,
pubmed-meshheading:20213810-Caspase 7,
pubmed-meshheading:20213810-Cells, Cultured,
pubmed-meshheading:20213810-Chondrocytes,
pubmed-meshheading:20213810-Down-Regulation,
pubmed-meshheading:20213810-Enzyme Inhibitors,
pubmed-meshheading:20213810-Humans,
pubmed-meshheading:20213810-Membrane Proteins,
pubmed-meshheading:20213810-Osteoarthritis,
pubmed-meshheading:20213810-RNA, Messenger,
pubmed-meshheading:20213810-RNA, Small Interfering,
pubmed-meshheading:20213810-Stress, Physiological,
pubmed-meshheading:20213810-Transfection,
pubmed-meshheading:20213810-Up-Regulation,
pubmed-meshheading:20213810-X-Linked Inhibitor of Apoptosis Protein
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pubmed:year |
2010
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pubmed:articleTitle |
ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis.
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pubmed:affiliation |
Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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