20213492

Source:http://linkedlifedata.com/resource/pubmed/id/20213492

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0010723, umls-concept:C0031327, umls-concept:C0045093, umls-concept:C0684249, umls-concept:C1516213, umls-concept:C1882417
pubmed:issue	6
pubmed:dateCreated	2010-5-13
pubmed:abstractText	To study the impact of the 79A>C polymorphism in the cytidine deaminase (CDA) gene on the pharmacokinetics of gemcitabine and its metabolite 2',2'-difluorodeoxyuridine (dFdU) in non-small-cell lung cancer (NSCLC) patients.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-10893285, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-11688520, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-11784875, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-12123338, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-1244564, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-12544510, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-14520444, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-16551864, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-1718594, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-17194903, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-18347182, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-18506025, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-19036079, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-1999720, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-20563566, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-2233693, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-3383195, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-7481842, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-7795789, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-8289286, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-9590659, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-9766663, http://linkedlifedata.com/resource/pubmed/commentcorrection/20213492-9878810
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/1256165
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/2',2'-difluoro-2'-deoxyuridine, http://linkedlifedata.com/resource/pubmed/chemical/Antimetabolites, Antineoplastic, http://linkedlifedata.com/resource/pubmed/chemical/Cytidine Deaminase, http://linkedlifedata.com/resource/pubmed/chemical/Deoxycytidine, http://linkedlifedata.com/resource/pubmed/chemical/Floxuridine, http://linkedlifedata.com/resource/pubmed/chemical/gemcitabine
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1432-1041
pubmed:author	pubmed-author:BoezenH MarikeHM, pubmed-author:GroenHarry J MHJ, pubmed-author:MaringJan GerardJG, pubmed-author:MaurerJ MarinaJM, pubmed-author:SlijferMoniqueM, pubmed-author:UgesDonald R ADR, pubmed-author:WachtersFloris MFM, pubmed-author:de VriesElisabeth G EEG
pubmed:issnType	Electronic
pubmed:volume	66
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	611-7
pubmed:dateRevised	2010-9-30
pubmed:meshHeading	pubmed-meshheading:20213492-Adult, pubmed-meshheading:20213492-Aged, pubmed-meshheading:20213492-Antimetabolites, Antineoplastic, pubmed-meshheading:20213492-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:20213492-Carcinoma, Non-Small-Cell Lung, pubmed-meshheading:20213492-Cytidine Deaminase, pubmed-meshheading:20213492-Deoxycytidine, pubmed-meshheading:20213492-Female, pubmed-meshheading:20213492-Floxuridine, pubmed-meshheading:20213492-Gene Frequency, pubmed-meshheading:20213492-Genotype, pubmed-meshheading:20213492-Humans, pubmed-meshheading:20213492-Lung Neoplasms, pubmed-meshheading:20213492-Male, pubmed-meshheading:20213492-Metabolic Clearance Rate, pubmed-meshheading:20213492-Middle Aged, pubmed-meshheading:20213492-Polymorphism, Single Nucleotide
pubmed:year	2010
pubmed:articleTitle	Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.
pubmed:affiliation	Department of Pharmacy, Diaconessen Hospital Meppel & Bethesda Hospital Hoogeveen, Hoogeveenseweg 38, 7943 KA, Meppel, The Netherlands. maring@noorderboog.nl
pubmed:publicationType	Journal Article, Clinical Trial, Phase III