Source:http://linkedlifedata.com/resource/pubmed/id/20211895
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-4-20
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pubmed:databankReference | |
pubmed:abstractText |
We have sequenced the conjugative plasmid pPR9, which carries the ileS2 gene, which had contributed to the dissemination of high-level mupirocin resistance at our institution. The plasmid backbone shows extensive genetic conservation with plasmids belonging to the pSK41/pGO1 family, but comparative analyses have revealed key differences that provide important insights into the evolution of these medically important plasmids and high-level mupirocin resistance in staphylococci and highlight the role of insertion sequence IS257 in these processes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1098-6596
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2252-7
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pubmed:dateRevised |
2010-11-2
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pubmed:meshHeading |
pubmed-meshheading:20211895-Anti-Bacterial Agents,
pubmed-meshheading:20211895-Chromosome Mapping,
pubmed-meshheading:20211895-Conjugation, Genetic,
pubmed-meshheading:20211895-Drug Resistance, Bacterial,
pubmed-meshheading:20211895-Drug Resistance, Multiple,
pubmed-meshheading:20211895-Genetic Heterogeneity,
pubmed-meshheading:20211895-Mupirocin,
pubmed-meshheading:20211895-Plasmids,
pubmed-meshheading:20211895-Staphylococcus aureus
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pubmed:year |
2010
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pubmed:articleTitle |
Complete nucleotide sequence and comparative analysis of pPR9, a 41.7-kilobase conjugative staphylococcal multiresistance plasmid conferring high-level mupirocin resistance.
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pubmed:affiliation |
Hospital Universitario Nuestra Señora de Candelaria, Departamento de Microbiología y Biología Celular, Universidad de La Laguna, La Laguna, Spain. eperroth@ull.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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