rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
1991-5-24
|
pubmed:abstractText |
The effect of olestra on vitamin D status was assessed in a 6-wk, double-blind, placebo-controlled study involving 202 free-living adults. Subjects consumed a total of 20 g/d of olestra or triglycerides in cookies eaten at each meal. A 20-micrograms ergocalciferol capsule was taken with each morning meal. Serum 25-hydroxyergocalciferol (25-OHD2) concentrations rose from approximately 5.7 to 39.0 and 31.7 nmol/L in the placebo and olestra groups, respectively, at week 6. At week 6, 25-OHD2 contributed 46-54% to total serum 25-OHD concentration compared with 11% at baseline. The 19% decrease in serum 25-OHD2 concentrations produced by olestra in this study is equivalent to a decrease of approximately 1.2 nmol/L under nonsupplemented dietary conditions. Ingesting 20 g olestra/d in the diet is thus not expected to affect vitamin D nutritional status.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0002-9165
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
53
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1281-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2021135-25-Hydroxyvitamin D 2,
pubmed-meshheading:2021135-Absorption,
pubmed-meshheading:2021135-Adult,
pubmed-meshheading:2021135-Anticholesteremic Agents,
pubmed-meshheading:2021135-Dietary Fats, Unsaturated,
pubmed-meshheading:2021135-Double-Blind Method,
pubmed-meshheading:2021135-Fatty Acids,
pubmed-meshheading:2021135-Female,
pubmed-meshheading:2021135-Humans,
pubmed-meshheading:2021135-Male,
pubmed-meshheading:2021135-Middle Aged,
pubmed-meshheading:2021135-Sucrose,
pubmed-meshheading:2021135-Vitamin D
|
pubmed:year |
1991
|
pubmed:articleTitle |
Serum 25-hydroxyvitamin D concentrations of free-living subjects consuming olestra.
|
pubmed:affiliation |
Procter & Gamble Company, Cincinnati, OH 45224.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|