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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5005
|
pubmed:dateCreated |
1991-5-30
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pubmed:abstractText |
The nematode Caenorhabditis elegans was transformed with constructs containing upstream deletions of the gut-specific ges-1 carboxylesterase gene. With particular deletions, ges-1 was expressed, not as normally in the gut, but rather in muscle cells of the pharynx (which belong to a sister lineage of the gut) or in body wall muscle and hypodermal cells (which belong to a cousin lineage of the gut). These observations suggest that gut-specific gene expression in C. elegans involves not only gut-specific activators but also multiple repressors that are present in particular nongut lineages.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0036-8075
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
26
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pubmed:volume |
252
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pubmed:geneSymbol |
ges-1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-82
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:2020855-Animals,
pubmed-meshheading:2020855-Caenorhabditis,
pubmed-meshheading:2020855-Carboxylesterase,
pubmed-meshheading:2020855-Carboxylic Ester Hydrolases,
pubmed-meshheading:2020855-Chromosome Deletion,
pubmed-meshheading:2020855-DNA,
pubmed-meshheading:2020855-Digestive System,
pubmed-meshheading:2020855-Embryo, Nonmammalian,
pubmed-meshheading:2020855-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:2020855-Models, Biological,
pubmed-meshheading:2020855-Organ Specificity
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pubmed:year |
1991
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pubmed:articleTitle |
Spatial control of gut-specific gene expression during Caenorhabditis elegans development.
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pubmed:affiliation |
Department of Medical Biochemistry, University of Calgary, Alberta, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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