Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-5-28
pubmed:abstractText
Cardiovascular responses to high-dose (0.100 IE kg-1 h-1) and low-dose insulin infusion (0.005-0.01 IE kg-1 h-1) were examined in eight hyperglycaemic, resting type I diabetics. Mean blood glucose dropped from 15.9 to 7.1 mmol l-1 and from 14.4 to 12.6 mmol l-1, respectively, during 1 h. Blood pressure and heart rate did not change. There were no significant changes in absolute or relative left ventricular volumes, the 95% confidence interval (CI) for the difference between the doses in left ventricular ejection fraction was -6 to 8%. Calf blood volume increased on high-dose insulin (p = 0.05, CI for the difference over low-dose insulin 0.0 to 4.6 ml 100 ml-1 tissue). Blood flow increased with 1.6 ml 100 ml-1 tissue min-1 with high-dose insulin and with 0.6 ml 100 ml-1 tissue min-1 with low-dose (CI for the difference -0.5 to 3.4). Noradrenaline increases were small and there was no difference between the doses (p = 0.47).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0036-5513
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
93-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Acute cardiovascular effects of insulin in hyperglycaemic type I diabetics.
pubmed:affiliation
Department of Clinical Physiology and Nuclear Medicine, Herlev Hospital, Denmark.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't