Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2011-2-14
pubmed:abstractText
The formation of hydroxyapatite is important for artificial materials to show high biological affinities for bone tissue. The present study focused on the synthesis of hydrogels capable of showing apatite formation, through modification of polyglutamic acid (PGA) with 3-aminopropyltriethoxysilane (APTES), followed by treatment with calcium chloride solution. A transparent bulk hydrogel was obtained at a molar ratio of PGA/APTES of 0.5. Prior soaking of the PGA hydrogel in calcium chloride solution accelerated the formation of bone-like apatite in a simulated body fluid. The modified PGA hydrogel is a candidate material for a biodegradable scaffold for bone regeneration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1530-8022
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
581-94
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Modification of polyglutamic acid with silanol groups and calcium salts to induce calcification in a simulated body fluid.
pubmed:affiliation
Graduate School of Engineering, Nagoya University, Furo-cho Chikusa-ku, Nagoya 464-8603, Japan. koh.miyoung@h.mbox.nagoya-u.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't