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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-10-27
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pubmed:abstractText |
Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiology of the disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1556-5653
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pubmed:author |
pubmed-author:HeLinL,
pubmed-author:LiBaojieB,
pubmed-author:ShiJuanziJ,
pubmed-author:WangLeiL,
pubmed-author:WangYingY,
pubmed-author:WebbS LSL,
pubmed-author:WeiZhiyunZ,
pubmed-author:XingQingheQ,
pubmed-author:ZhangXiaopingX,
pubmed-author:ZhaoAmanA,
pubmed-author:ZhaoXinzhiX
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pubmed:copyrightInfo |
Crown Copyright © 2010. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2486-9, 2489.e1-2
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20207350-Adult,
pubmed-meshheading:20207350-Case-Control Studies,
pubmed-meshheading:20207350-Female,
pubmed-meshheading:20207350-Gene Frequency,
pubmed-meshheading:20207350-Genetic Predisposition to Disease,
pubmed-meshheading:20207350-Genetic Variation,
pubmed-meshheading:20207350-Glucose,
pubmed-meshheading:20207350-Glucose Intolerance,
pubmed-meshheading:20207350-Glucose Tolerance Test,
pubmed-meshheading:20207350-Humans,
pubmed-meshheading:20207350-Insulin,
pubmed-meshheading:20207350-Phenotype,
pubmed-meshheading:20207350-Polycystic Ovary Syndrome,
pubmed-meshheading:20207350-Polymorphism, Single Nucleotide,
pubmed-meshheading:20207350-Receptor, Melatonin, MT2,
pubmed-meshheading:20207350-Testosterone
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pubmed:year |
2010
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pubmed:articleTitle |
Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients.
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pubmed:affiliation |
Institutes of Biomedical Science, Fudan University, Shanghai, People's Republic of China. wangleiwanglei@fudan.edu.cn
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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