rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
7
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pubmed:dateCreated |
2010-6-10
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pubmed:abstractText |
Circulating platelet counts gradually decrease in parallel with progression of chronic liver disease. Thrombocytopenia is a common complication of advanced liver fibrosis and is thought to be a consequence of the destruction of circulating platelets that occurs during secondary portal hypertension or hypersplenism. It is not clear whether thrombocytopenia itself affects liver fibrosis.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1528-0012
|
pubmed:author |
pubmed-author:FuY PYP,
pubmed-author:HayashiNorioN,
pubmed-author:HikitaHayatoH,
pubmed-author:HosuiAtsushiA,
pubmed-author:IdoAkioA,
pubmed-author:IshidaHisashiH,
pubmed-author:KodamaTakahiroT,
pubmed-author:MiyagiTakuyaT,
pubmed-author:ShimizuSatoshiS,
pubmed-author:TadokoroSeijiS,
pubmed-author:TakeharaTetsuoT,
pubmed-author:TatsumiTomohideT,
pubmed-author:TsubouchiHirohitoH
|
pubmed:copyrightInfo |
Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
138
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2487-98, 2498.e1-7
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pubmed:dateRevised |
2011-6-2
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pubmed:meshHeading |
pubmed-meshheading:20206174-Animals,
pubmed-meshheading:20206174-Cholestasis,
pubmed-meshheading:20206174-Collagen,
pubmed-meshheading:20206174-Hepatocyte Growth Factor,
pubmed-meshheading:20206174-Liver Cirrhosis, Experimental,
pubmed-meshheading:20206174-Mice,
pubmed-meshheading:20206174-Mice, Inbred C57BL,
pubmed-meshheading:20206174-Mice, Knockout,
pubmed-meshheading:20206174-Platelet Activation,
pubmed-meshheading:20206174-Thrombocytopenia,
pubmed-meshheading:20206174-bcl-X Protein
|
pubmed:year |
2010
|
pubmed:articleTitle |
Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice.
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pubmed:affiliation |
Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|