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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-3-8
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pubmed:abstractText |
Tumor eradication by chemoradiotherapy for pharyngeal cancer has not been particularly successful. Targeting epithelial growth factor receptor (EGFR) could be a potential treatment strategy providing additional benefits, but only a subset of these tumors gives a clinically significant response to EGFR inhibitors. The aim has been to identify the role of interleukin-6 (IL-6) signaling and its predictive power in the treatment response of pharyngeal cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/cetuximab
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1879-355X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1214-24
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pubmed:meshHeading |
pubmed-meshheading:20206020-Adult,
pubmed-meshheading:20206020-Aged,
pubmed-meshheading:20206020-Aged, 80 and over,
pubmed-meshheading:20206020-Antibodies, Monoclonal,
pubmed-meshheading:20206020-Antineoplastic Agents,
pubmed-meshheading:20206020-Carcinoma, Squamous Cell,
pubmed-meshheading:20206020-Cell Line, Tumor,
pubmed-meshheading:20206020-Cell Nucleus,
pubmed-meshheading:20206020-Humans,
pubmed-meshheading:20206020-Interleukin-6,
pubmed-meshheading:20206020-Middle Aged,
pubmed-meshheading:20206020-Multivariate Analysis,
pubmed-meshheading:20206020-Neoplasm Proteins,
pubmed-meshheading:20206020-Pharyngeal Neoplasms,
pubmed-meshheading:20206020-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:20206020-Radiation Tolerance,
pubmed-meshheading:20206020-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20206020-Receptors, Interleukin-6,
pubmed-meshheading:20206020-STAT3 Transcription Factor,
pubmed-meshheading:20206020-Signal Transduction
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pubmed:year |
2010
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pubmed:articleTitle |
Significance of interleukin-6 signaling in the resistance of pharyngeal cancer to irradiation and the epidermal growth factor receptor inhibitor.
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pubmed:affiliation |
Department of Hematology and Oncology, Chang Gung Memorial Hospital at Chiayi, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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