Microneedles are small-scale devices that are finding use for transdermal delivery of protein-based pharmacologic agents and nucleic acid-based pharmacologic agents; however, microneedles prepared using conventional microelectronics-based technologies have several shortcomings, which have limited translation of these devices into widespread clinical use.
University of North Carolina Chapel Hill and North Carolina State University, Joint Department of Biomedical Engineering, CB 7115, 2147 Burlington Labs, Raleigh, NC 27695, USA.