|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005682,
umls-concept:C0030685,
umls-concept:C0078058,
umls-concept:C0162337,
umls-concept:C0205178,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C1171892,
umls-concept:C1283071,
umls-concept:C1514873,
umls-concept:C1546857,
umls-concept:C1556066,
umls-concept:C1619636,
umls-concept:C1963578
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|
pubmed:issue |
9
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|
pubmed:dateCreated |
2010-10-15
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|
pubmed:abstractText |
To investigate the corticotropin-releasing hormone (CRH) receptor (CRH-R) requirement for the effect of acute stress on bladder vascular permeability and release of vascular endothelial growth factor (VEGF), as increasing evidence indicates that acute stress worsens certain inflammatory disorders, including interstitial cystitis/painful bladder syndrome (IC/PBlS), which is characterized by pain, variable bladder inflammation, increased expression of bladder vascular endothelial growth factor (VEGF), and many detrusor mast cells.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
|
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
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pubmed:issn |
1464-410X
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 THE AUTHORS. JOURNAL COMPILATION © 2010 BJU INTERNATIONAL.
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pubmed:issnType |
Electronic
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1394-9
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pubmed:meshHeading |
pubmed-meshheading:20201838-Acute Disease,
pubmed-meshheading:20201838-Animals,
pubmed-meshheading:20201838-Capillary Permeability,
pubmed-meshheading:20201838-Cystitis, Interstitial,
pubmed-meshheading:20201838-Female,
pubmed-meshheading:20201838-Immunohistochemistry,
pubmed-meshheading:20201838-Mast Cells,
pubmed-meshheading:20201838-Mice,
pubmed-meshheading:20201838-Mice, Inbred C57BL,
pubmed-meshheading:20201838-Mice, Knockout,
pubmed-meshheading:20201838-Receptors, Corticotropin-Releasing Hormone,
pubmed-meshheading:20201838-Stress, Psychological,
pubmed-meshheading:20201838-Vascular Endothelial Growth Factor A
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pubmed:year |
2010
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pubmed:articleTitle |
Corticotropin-releasing hormone-receptor 2 is required for acute stress-induced bladder vascular permeability and release of vascular endothelial growth factor.
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pubmed:affiliation |
Molecular Immunopharmacology and Drug Discovery Laboratory, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA 02111, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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